REGULAR ARTICLES
Cell Research (1997)7:51-59
© 1997 SIBS, CAS All rights reserved 1001-0602/97
Identification and expression of epidermal growth factor gene
in mouse testis.
Zhang ML, Yan YC, Sun YP, Koide SS.
Shanghai Institute of Cell Biology, Chinese Academy of Sciences,
China.
Correspondence:
Yan YC |
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Yan YC
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Epidermal growth factor (EGF) is produced primarily by Leydig cells of human
testis. Expression of the EGF gene was assessed in mouse testis during the
course of sexual maturation by the application of the RT-PCR method and
the use of specific oligonucleotide primers. Testis EGF mRNA content increased
with the developmental age of the mice, i.e., day 15 < day 30 < day
45 postnatal. The expression of the EGF gene appears to correlate with maturation
of the testis and proliferation of Leydig-cells.
Keywords : Epidermal
growth factor, testis, gene expression, spermatogenesis, sexual maturation. |
