COMMENTARY
Cell Research (1998)8:99-103
© 1998 SIBS, CAS All rights reserved 1001-0602/98
On the history of nuclear matrix manifestation.
Ib Z.
N.K. Koltzov Institute of Developmental Biology, Russian Academy
of Sciences, Moscow, Russia. ibzba@ibrran.msk.su
Correspondence:
Ib Z.
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Ib Z.
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The nonchromatin proteinous residue of the cell nucleus was revealed in
our laboratory as early as in 1948 and then identified by light and electron
microscopy as residual nucleoli, intranuclear network and nuclear envelope
before 1960. This structure termed afterwards as "nuclear residue",
"nuclear skeleton", "nuclear cage", "nuclear carcass"
etc., was much later (in 1974) isolated, studied and entitled as "nuclear
matrix" by Berezney and Coffey, to whom the discovery of this residual
structure is often wrongly ascribed. The real history of nuclear matrix
manifestation is reported in this paper.
Keywords : Nuclear
matrix, nuclear residue, nuclear fractions, history or nuclear fractionation. |
