MINIREVIEWS

Cell Research, 15(1):33-35, Jan 2005

Role of c-Abl in the DNA damage stress response

Yosef SHAUL^*, Merav BEN-YEHOYADA

Department of Molecular Genetics, Weizmann Institute of Scienc, Rehovot 76100, Israel

Correspondence: Yosef SHAUL +972-8-934-2320 (phone) yosef.shaul@weizmann.ac.il

Table of Contents Download as printable (PDF) file -122K Full Text (html)file Search Medline for articles by: Yosef SHAUL

Abstract

c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. Here we briefly review the current knowledge about c-Abl involvement in the DNA-damage stress response and its implication on cell physiology.

Keywords: c-Abl, DNA-damage.