ORIGINAL ARTICLE

Cell Research (2006)16:446-456
© 2006 IBCB, SIBS, CAS All rights reserved 1001-0602/06 $ 30.00
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BUD2, encoding an S-adenosylmethionine decarboxylase, is required for Arabidopsis growth and development

Chunmin Ge, Xia Cui, Yonghong Wang, Yuxin Hu, Zhiming Fu, Dongfen Zhang, Zhukuan Cheng, Jiayang Li

¹State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; 2Graduate School, Chinese Academy of Sciences, Beijing 100101, China; 3Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China

*These authors contributed equally to this work. Correspondence: Jiayang Li Tel: 86-10-64852855; Fax: 86-10-64873428; E-mail: jyli@genetics.ac.cn Received 10 Jan 2006; revised 20 Feb 2006; accepted 26 Feb 2006; published online 15 May 2006

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Polyamines are implicated in regulating various developmental processes in plants, but their exact roles and how they govern these processes still remain elusive. We report here an Arabidopsis bushy and dwarf mutant, bud2, which results from the complete deletion of one member of the small gene family that encodes S-adenosylmethionine decarboxylases (SAMDCs) necessary for the formation of the indispensable intermediate in the polyamine biosynthetic pathway. The bud2 plant has enlarged vascular systems in inflorescences, roots, and petioles, and an altered homeostasis of polyamines. The double mutant of bud2 and samdc1, a knockdown mutant of another SAMDC member, is embryo lethal, demonstrating that SAMDCs are essential for plant embryogenesis. Our results suggest that polyamines are required for the normal growth and development of higher plants.

Cell Research (2006) 16:446-456. doi:10.1038/sj.cr.7310056; published online 15 May 2006

Keywords: BUD2, polyamines, embryogenesis, plant architecture, Arabidopsis