A special issue on DNA damage responses and genome maintenance
Guo-Min Li, David J Chen, Sankar Mitra and John J Turchi

A brief history of the DNA repair field
Errol C Friedberg

The DNA damage response pathways: at the crossroad of protein modifications
Michael SY Huen and Junjie Chen

DNA damage-induced cell death: lessons from the central nervous system
Helena Lobo Borges, Rafael Linden and Jean YJ Wang

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
Muralidhar L Hegde, Tapas K Hazra and Sankar Mitra

XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks
Julie K Horton, Mary Watson, Donna F Stefanick, Daniel T Shaughnessy, Jack A Taylor and Samuel H Wilson

Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
Sarah C Shuck, Emily A Short and John J Turchi

Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects
Maria Fousteri and Leon HF Mullenders

Mechanisms and functions of DNA mismatch repair
Guo-Min Li

Homologous recombination in DNA repair and DNA damage tolerance
Xuan Li and Wolf-Dietrich Heyer

The endless tale of non-homologous end-joining
Eric Weterings and David J Chen

Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune system
Michael R Lieber, Haihui Lu, Jiafeng Gu and Klaus Schwarz

Regulation of DNA double-strand break repair pathway choice
Meena Shrivastav, Leyma P De Haro and Jac A Nickoloff

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
Scott D McCulloch and Thomas A Kunkel

Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA
Parker L Andersen, Fang Xu and Wei Xiao

DNA polymerase zeta (polζ) in higher eukaryotes
Gregory N Gan, John P Wittschieben, Birgitte Ø Wittschieben and Richard D Wood

Structure and mechanism for DNA lesion recognition
Wei Yang

Features of trinucleotide repeat instability in vivo
Irina V Kovtun and Cynthia T McMurray