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Vol.20 No.2 2010


[Cover Caption]

  RESEARCH HIGHLIGHTS PAGE
 

Histone code in the cross-talk during DNA damage signaling
Thomas Vaissière and Zdenko Herceg

113-115
  [Abstract]
 
     
 

Novel molecular insights into the mechanism of GO removal by MutM
Guo-Min Li

116-118
  [Abstract]
 
     
 

Slaying RAS with a synthetic lethal weapon
Archana Bommi-Reddy and William G Kaelin Jr

119-121
  [Abstract]
 
     
 

UnTTrapping the ends: A new player in overcoming protein linked DNA damage
Karim Bahmed, Karin C Nitiss and John L Nitiss

122-123
  [Abstract]  
     
  REVIEW PAGES
 

PPARs: diverse regulators in energy metabolism and metabolic diseases
Yong-Xu Wang

124-137
  [Abstract]    
     
  ORIGINAL ARTICLES PAGES
 

A GPCR/secretase complex regulates β- and γ-secretase specificity for Aβ production and contributes to AD pathogenesis
Lin Teng, Jian Zhao, Feifei Wang, Lan Ma and Gang Pei

138-153
  [Abstract]    
     
 

Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4
Chengyang Huang, Yang Xiang, Yanru Wang, Xia Li, Longyong Xu, Ziqi Zhu, Ting Zhang, Qingqing Zhu, Kejing Zhang, Naihe Jing and Charlie Degui Chen

154-165
  [Abstract]    
     
 

Structural insights into a novel histone demethylase PHF8
Lin Yu, Yang Wang, Shuo Huang, Jianjun Wang, Zengqin Deng, Qi Zhang, Wei Wu, Xingliang Zhang, Zhao Liu, Weimin Gong and Zhongzhou Chen

166-173
  [Abstract]    
     
 

ATF4 regulates lipid metabolism and thermogenesis
Chunxia Wang, Zhiying Huang, Ying Du, Ying Cheng, Shanghai Chen and Feifan Guo

174-184
  [Abstract]    
     
 

Small ubiquitin-related modifier paralogs are indispensable but functionally redundant during early development of zebrafish
Hao Yuan, Jun Zhou, Min Deng, Xi Liu, Morgane Le Bras, Hugues de The, Sai Juan Chen, Zhu Chen, Ting Xi Liu and Jun Zhu

185-196
  [Abstract]    
     
 

High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans
Xing-Jun Cao, Jie Dai, Hao Xu, Song Nie, Xiao Chang, Bao-Yu Hu, Quan-Hu Sheng, Lian-Shui Wang, Zhi-Bin Ning, Yi-Xue Li, Xiao-Kui Guo, Guo-Ping Zhao and Rong Zeng

197-210
  [Abstract]    
     
 

Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity
Min Luo, Zhiyong Lu, He Sun, Kehu Yuan, Quancang Zhang, Sha Meng, Fangxun Wang, Hongchun Guo, Xiaofang Ju, Yuqing Liu, Tao Ye, Zhigang Lu and Zhonghe Zhai

211-222
  [Abstract]    
     
 

Endocytosis of FcαR is clathrin and dynamin dependent, but its cytoplasmic domain is not required
Min Peng, Na Yin and Wei Zhang

223-237
  [Abstract]    
     
  LETTERS TO THE EDITOR PAGES
 

Netrin-1 signaling mediates NO-induced glial precursor migration and accumulation
Hongwei Chen, Qiang Wei, Jing Zhang, Chuangkun Xu, Tao Tan and Weizhi Ji

238-241
  [Abstract]    
     
 

Activation of JNK signaling links lgl mutations to disruption of the cell polarity and epithelial organization in Drosophila imaginal discs
Mingwei Zhu, Tianchi Xin, Shunyan Weng, Yin Gao, Yingjie Zhang, Qi Li and Mingfa Li

242-245
  [Abstract]    
     

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