Advanced Search
Submit ManuscriptADVANCE ONLINE PUBLICATION
An exploitable Achilles heel of MITF?
Carolina Silva1,2 , Ze’ev A. Ronai1,*
1Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USAMicrophthalmia-associated transcription factor (MITF) has been implicated in melanoma development and progression. In a study published in Cell Research, Liu et al. suggest that inhibition of MITF via targeting of its dimer interface may provide a novel therapeutic modality.
https://doi.org/10.1038/s41422-022-00762-3