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Precision medicine for metastatic TNBC: the FUTURE is now

Julia Foldi1 , Charles E. Geyer Jr1,2,*

1Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center, Pittsburgh, PA, USA
2NSABP Foundation, Pittsburgh, PA, USA
* Correspondence: Charles E. Geyer Jr(charles.geyer@nsabp.org)

Despite well-described molecular heterogeneity of triple negative breast cancer (TNBC), management of metastatic disease primarily relies on cytotoxic chemotherapies, in some cases combined with immunotherapy, without consideration of molecular subtypes. In a recent Cell Research article, Liu et al. show the feasibility and promise of a precision medicine-guided treatment approach for heavily pretreated metastatic TNBC.

https://doi.org/10.1038/s41422-023-00815-1

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