ISSN: 1001-0602
EISSN: 1748-7838
2012 impact factor 10.526*
(Thomson Reuters, 2013)
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VOLUME 27 ISSUE 8(8,2017): 965-966

 

It takes two to transport via an elevator

 

Bernadette Byrne1

 

1Department of Life Sciences, Imperial College London, London SW7 2AZ, UK

Correspondence:Bernadette Byrne,        

E-mail: b.byrne@imperial.ac.uk

 

Membrane transporter proteins are critical for cellular uptake and export of molecules, and are reported to function by a number of different molecular mechanisms. The new occluded state structure of the uracil transporter, UraA, from Escherichia coli, reveals that both coordinated movement of the two domains of a single protomer together with dimer formation are important for transport activity.

 

10.1038/cr.2017.89

 
 
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