ISSN: 1001-0602
EISSN: 1748-7838
2012 impact factor 10.526*
(Thomson Reuters, 2013)
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VOLUME 27 ISSUE 8(8,2017): 1074-1074

 

RIPped for neuroinflammation FREE

 

Bart Tummers1 and Douglas R Green1

 

1Department of Immunology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA

Correspondence:Douglas R Green,        

E-mail: douglas.green@stjude.org

 

Activation of the receptor interacting serine/threonine kinase (RIPK) 3 mediates an inflammatory type of cell death called necroptosis; in addition, RIPK3 has necroptosis-independent roles in inflammation, although these are not well defined. In a recent study published in Cell, Daniels and colleagues demonstrate that RIPK3 controls West Nile virus infection by promoting neuroinflammation in the central nervous system without affecting neuronal death.

 

10.1038/cr.2017.75

 
 
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