ISSN: 1001-0602
EISSN: 1748-7838
2012 impact factor 10.526*
(Thomson Reuters, 2013)
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VOLUME 28 ISSUE 10(10,2018): 963-964

 

Guiding a mutator in antibody diversification

 

Ming Tian 1 and Frederick W. Alt 1

 

1Boston Children’s Hospital, Harvard Medical School, HHMI, Boston, MA 02115, USA

Correspondence:Correspondence: Ming Tian (Ming_Tian@hms.harvard.edu)        

 

Activation Induced Cytidine Deaminase is a mutator that is essential for antibody diversification. A new study, recently reported in Cell Research , provides insights into the mechanism that guides the mutator to physiological targets.

 

https://doi.org/10.1038/s41422-018-0085-8

 
 
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