AOP Jing Wu, Rongqi Duan, Huibi Cao, Deborah Field, Catherine M Newnham, David R Koehler, Noe Zamel, Melanie A Pritchard, Paul Hertzog, Martin Post, A Keith Tanswell and Jim Hu REVIEWS Kathleen Kelly and Juan Juan Yin
Genomic analysis of epithelial ovarian cancer ORIGINAL ARTICLES Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors
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Vol 18, No 5, 2008 ISSN: 1001-0602 2006 impact factor 3.426* (ISI, Thomson 2007) |
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| Research Highlights | ||||
| Feb issue | Feb issue | |||
More new lines of human parthenogenetic embryonic stem cellsLinzhao Cheng |
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Cyclin B1: conductor of mitotic symphony orchestraHuijuan Yu and Xuebiao Yao |
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Two papers published in a recent issue of Cell Research describe the derivation of pluripotent human embryonic stem (hES)-like cell lines from parthenogeneic blastocysts. These two papers complement and substantiate two other papers published a few months earlier, which described seemingly two classes of pathenogenetic hES cell lines. Together, these 4 papers mark the beginning of a new era in hES cell research: parthenogenetic hES cell lines come of age. |
In this issue of Cell Research, Zhang and his colleagues, in an effort to delineate the function of cyclin B1 in mitosis, carried out a thorough analysis of cyclin B1 distribution in mammalian cells. They demonstrated that cyclin B1 is preferentially localized to unattached kinetochores and involved in chromosome alignment in mitosis. In addition, they provided evidence that the CDK1 population at kinetochores is in fact active and that the abundance of the complex varies during mitotic progression. |
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| Focus Highlights | ||
Focus issues on "cell signaling Review Series" Totally eight review articles focus on cell signalling are published in three issues. We hope that our readers find these papers useful to their research. May 2008; 18(5):523-548. |
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Editorial: A special issue on DNA damage responses and genome maintenance In this special issue, Cell Research presents a series of reviews covering cellular mechanisms that ensure the integrity of the genome. There are two classes of genome-maintenance systems, one responsible for accurately propagating the genetic information in DNA, and the other responsible for proper processing of DNA damage caused by various endogenous and exogenous agents. This issue has been highlighted on nature.com as a special feature. |
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We collected several review articles for RNA and shared with our readers. More papers about this issue will be added to this collcetion. |
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Editorial: Cancer research in China: a Special Focus by Cell Research The year of 2007 is the 100th anniversary of the American Association for Cancer Research (AACR), "marking a century of progress in saving lives through cancer research" (quote from the AACR website). Along with the rapid pace of growth of scientific research in China, the field of cancer research has also seen more and more prominent contributions by Chinese scientists. The editors of Cell Research, China's premium international journal in life sciences, have selected a number of outstanding papers on cancer research that have come out of China in the last few years to be the subject of commentaries by the authors of these articles. |
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Editorial: A special issue on "Stem Cel" Stem cells possess the remarkable ability of extensive self-renewal and differentiation into specific cell lineages, and they play essential roles in development and adult tissue homeostasis. Due to their critical importance in normal physiology and the promise for use in regenerative medicine to treat a variety of diseases, stem cells have attracted extensive research interest in recent years. As China's premium international journal with a broad scope in cell and molecular biology, Cell Research has witnessed more and more submissions on stem cell research. Indeed, along with the traditional strengths of the journal in molecular immunology, cancer biology, and plant molecular physiology, stem cell research has gradually and naturally evolved into a new growth point of Cell Research. Reflecting the growing interest of both our readers and authors in this exciting and expanding field, we are pleased to present this Special Issue on Stem Cell Research. |
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Editorial: A special issue on "Plant Molecular Biology" The use of molecular biology and genomics tools in plant biology research has greatly expanded our understanding of the molecular mechanisms that underlie plant development and physiology. The successful establishment of research resources such as mutant populations has led to progress in a variety of fields, including plant reproductive development, signal transduction, hormone functions, defense responses and epigenetic control. In the future these advances will potentially facilitate crop improvement through molecular breeding. In conjunction with the successful "International Conference on the Frontiers of Plant Molecular Biology, Chinese Academy of Sciences (2005)" recently held in Shanghai (27-29th, Oct, 2005), Cell Research is pleased to publish a special issue on "Plant Molecular Biology". |
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Editorial: A special issue on "Interferons, Cytokines, and Immunity" Vertebrates including human employ both innate and adaptive immune responses to defend against pathogen infections and malignancy. Interferons and cytokines play pivotal roles in mediating and coordinating diverse aspects of the host immune response responsible for the clearance of infection and elimination of malignant cells. In addition, abnormal immune and/or inflammatory responses are closely linked to the pathogenesis of various human diseases such as infections, autoimmune diseases and cancer. Thus, a better understanding of these signaling pathways is essential to our efforts in developing more effective regimes to prevent and treat infectious diseases as well as to combat autoimmune diseases and cancer. In conjunction with the successful hosting of the 2005 Annual Meeting of the International Society for Interferon and Cytokine Research (ISICR) in Shanghai (10/20 - 10/24/2005), Cell Research is pleased to bring to our readers a special issue on "Interferon, Cytokine, and Immunity." |
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| Noticeboard | |||
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Congratulations for the successfully holding of the 5th Asian-Pacific Organization for Cell Biology Congress (APOCB 2006) in Beijing from Oct 28 to 30, 2006, China. The abstracts launched on Dec 29, 2006! | ||









