Cell Research

AOP
Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions(FREE)
Zhen Bian, Li-Min Li, Rui Tang, Dong-Xia Hou, Xi Chen, Chen-Yu Zhang and Ke Zen

REVIEW
Molecular basis of the first cell fate determination in mouse embryogenesis(FREE)
Lingyi Chen, Dekun Wang, Zhaoting Wu, Liping Ma and George Q Daley

ORIGINAL ARTICLES
Tom70 mediates activation of interferon regulatory factor 3 on mitochondria(FREE)
Xin-Yi Liu, Bo Wei, He-Xin Shi, Yu-Fei Shan and Chen Wang

Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement
Xin Lu, Xuemin Lu and Yibin Kang

PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130
Zhongwei Zhou, Xiaotian Sun, Zhenhua Zou, Litao Sun, Tao Zhang, Shaoshi Guo, Ya Wen, Lin Liu, Yi Wang, Jun Qin, Lei Li, Weimin Gong and Shilai Bao

High-efficiency somatic reprogramming induced by intact MII oocytes
Hui Yang, Linyu Shi, Shenghua Zhang, Jiangwei Ling, Jing Jiang and Jinsong Li

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Vol 20, No 9, 2010

ISSN: 1001-0602
EISSN: 1748-7838

2009 impact factor 8.151*

(ISI, Thomson Reuters, 2010)
21/161 Cell Biology

Editorial: A special issue on TGF-β signaling

TGF-β-initiated signaling is undoubtedly one of the most important and well investigated signaling events as TGF-β controls cell proliferation, differentiation, death and motility, and therefore plays an essential role in embryonic patterning and homeostasis of adult tissues. Deregulation of TGF-β signaling has been shown to be associated with several major diseases. Much has been learnt about the Smad-mediated canonical TGF-β signaling pathway in the last decade. However, modulation of this pathway via regulation of protein stability and subcellular localization, the crosstalk between the TGF-β/Smad pathway and other signaling pathways, and Smad-independent TGF-β signaling pathways just starts to become clear. This special issue presents 10 review articles covering current understanding of these major issues as well as the physiological and pathological roles of TGF-β in stem cell self-renewal, cell differentiation, angiogenesis and cancer metastasis.

Focus issues on "cell signaling Review Series"

Totally eight review articles focus on cell signalling are published in three issues. We hope that our readers find these papers useful to their research.

May 2008; 18(5):523-548.
Apr 2008; 18 (4):436 - 457.
Mar 2008; 18 (3):334 - 349.

Editorial: A special issue on DNA damage responses and genome maintenance

In this special issue, Cell Research presents a series of reviews covering cellular mechanisms that ensure the integrity of the genome. There are two classes of genome-maintenance systems, one responsible for accurately propagating the genetic information in DNA, and the other responsible for proper processing of DNA damage caused by various endogenous and exogenous agents.

This issue has been highlighted on nature.com as a special feature.

A focus issue on "RNA"

We collected several review articles for RNA and shared with our readers. More papers about this issue will be added to this collcetion.

Editorial: Cancer research in China: a Special Focus by Cell Research

The year of 2007 is the 100th anniversary of the American Association for Cancer Research (AACR), "marking a century of progress in saving lives through cancer research" (quote from the AACR website). Along with the rapid pace of growth of scientific research in China, the field of cancer research has also seen more and more prominent contributions by Chinese scientists. The editors of Cell Research, China's premium international journal in life sciences, have selected a number of outstanding papers on cancer research that have come out of China in the last few years to be the subject of commentaries by the authors of these articles.

Editorial: A special issue on "Stem Cell"

Stem cells possess the remarkable ability of extensive self-renewal and differentiation into specific cell lineages, and they play essential roles in development and adult tissue homeostasis. Due to their critical importance in normal physiology and the promise for use in regenerative medicine to treat a variety of diseases, stem cells have attracted extensive research interest in recent years. As China's premium international journal with a broad scope in cell and molecular biology, Cell Research has witnessed more and more submissions on stem cell research. Indeed, along with the traditional strengths of the journal in molecular immunology, cancer biology, and plant molecular physiology, stem cell research has gradually and naturally evolved into a new growth point of Cell Research. Reflecting the growing interest of both our readers and authors in this exciting and expanding field, we are pleased to present this Special Issue on Stem Cell Research.

Editorial: A special issue on "Plant Molecular Biology"

The use of molecular biology and genomics tools in plant biology research has greatly expanded our understanding of the molecular mechanisms that underlie plant development and physiology. The successful establishment of research resources such as mutant populations has led to progress in a variety of fields, including plant reproductive development, signal transduction, hormone functions, defense responses and epigenetic control. In the future these advances will potentially facilitate crop improvement through molecular breeding. In conjunction with the successful "International Conference on the Frontiers of Plant Molecular Biology, Chinese Academy of Sciences (2005)" recently held in Shanghai (27-29th, Oct, 2005), Cell Research is pleased to publish a special issue on "Plant Molecular Biology".