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Maternally loaded RNAs: no time to die

Martino Ugolini , Nadine L. Vastenhouw

Center for Integrative Genomics (CIG), University of Lausanne (UNIL), Lausanne, Switzerland
* Correspondence: Nadine L. Vastenhouw(nadine.vastenhouw@unil.ch)

Upon fertilization, the animal genome is often inactive and development is driven by proteins and transcripts that are stored in the egg during oogenesis. In a recent Cell Research paper, Shi et al. show that the RNA helicase Ddx3xb facilitates the translation of stored transcripts in zebrafish embryos by a phase separation-dependent process.

https://doi.org/10.1038/s41422-022-00670-6

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