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Submit Manuscript ISSN: 1001-0602
EISSN: 1748-7838
2020 impact factor 25.617*
(Clarivate Analytics, 2021)
About the cover
A study revealed that SARS-CoV-2 generates Z-RNA during virus infection. The left-handed Z-RNA ignites ZBP1-RIPK3-MLKL necroptosis pathway. The RIPK3 scaffolding functionality additionally promotes chemokine production to magnify the inflammatory responses. These synergistically lead to SARS-CoV-2-triggered lung damage and COVID-19. See page 201–214 by Shufen Li et al. for details.
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SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responsesLETTERS TO THE EDITOR
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