Volume 32, No 6, Jun 2022

ISSN: 1001-0602 
EISSN: 1748-7838  
2020 impact factor 25.617*  
(Clarivate Analytics, 2021)

About the cover

Radiotherapy (light provided by electricity infrastructure) combined with VEGF-C that augments MLVs (roads constructed by road construction team) together promotes antigen-presenting DC trafficking (locally grown fruits transported by truck), resulting in effective glioma treatment (poverty elimination). See pages 543-554 by Changping Zhou et al. for details.

Advanced Online Publication: 24 Jun 2022

ORIGINAL ARTICLES

Transcriptome dynamics of hippocampal neurogenesis in macaques across the lifespan and aged humans

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Current Issue: Vol.32 (Jun 2022)

RESEARCH HIGHLIGHTS

Amplifying natural antitumor immunity for personalized immunotherapy
PEN2: Metformin’s new partner at lysosome
Krebs and an alternative TCA cycle!
Nuclear tetraspanin 8 promotes breast cancer progression

ORIGINAL ARTICLES

Derivation of totipotent-like stem cells with blastocyst-like structure forming potential
Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy response
Meningeal lymphatics regulate radiotherapy efficacy through modulating anti-tumor immunity
Gut microbiota drives macrophage-dependent self-renewal of intestinal stem cells via niche enteric serotonergic neurons
Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity

LETTERS TO THE EDITOR

Generic amyloid fibrillation of TMEM106B in patient with Parkinson’s disease dementia and normal elders
Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo
Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction
Synthetic lethal screening identifies DHODH as a target for MEN1-mutated tumor cells

CORRIGENDA

Author Correction: Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2