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ISSN: 1001-0602
EISSN: 1748-7838
2020 impact factor 25.617*
(Clarivate Analytics, 2021)
About the cover
A martini glass serves as a conceptual lens into human blastoid formation. Pluripotent stem cells on the left transition, under the influence of a single small molecule, DMSO, into a fluid-filled blastoid on the right. At the center, fruit-slice-like cellular cross-sections depict lysosome-like “seeds”, where DMSO enhances lysosomal acidification via V-ATPase-mediated proton transport in outer trophectoderm cells. This process drives the osmotic cascade underlying blastocyst cavitation. See page 475–498 by Samhan Alsolami et al. for details.
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