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Dietary fibers & immunity—more than meets the eye

Yotam Cohen¹ , Eran Elinav^1,2,*

¹Systems Immunology Department, Weizmann Institute of Science, Rehovot, Israel
²Division of Microbiome & Cancer, DKFZ, Heidelberg, Germany
* Correspondence: Eran Elinav(eran.elinav@weizmann.ac.il)

Dietary fiber consumption is suggested to favorably impact immune function, but the mechanisms mediating this effect remain under explored. In a recent study in Nature, Arifuzzaman et al. unveil that murine consumption of a specific dietary fiber, inulin, induces type 2 inflammatory responses, through discrete microbiome-mediated mechanisms; these dietary-induced immune responses, in turn, modulate context-dependent detrimental or beneficial inflammatory consequences in the mammalian host.

https://doi.org/10.1038/s41422-022-00770-3

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