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Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex

Yunxia Xu^1,† , Yaqi Wu^1,† , Yuanyuan Zhang^1,† , Ruixin Fan¹ , Yaxue Yang¹ , Danyang Li² , Shimin Zhu¹ , Biao Yang¹ , Zhengyu Zhang^1,* , Changjiang Dong^1,*

¹Department of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, State Key Laboratory of Virology, School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei, China
²The Cryo-EM Center, Core facility of Wuhan University, Wuhan University, Wuhan, Hubei, China
^†These authors contributed equally: Yunxia Xu, Yaqi Wu, Yuanyuan Zhang
* Correspondence: Zhengyu Zhang(zhengyu.zhang@whu.edu.cn)Changjiang Dong(changjiangdong@whu.edu.cn)

https://doi.org/10.1038/s41422-023-00796-1

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