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RNA editing: new roles in feedback and feedforward control
Xiang-Dong Fu
Westlake Laboratory of Life Sciences and Biomedicine, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, ChinaBiological systems use a variety of feedback and feedforward mechanisms to establish and maintain specific cellular programs. In a recent study published in Cell Research, Lin et al. add RNA editing to an S-nitrosylation-induced feedforward process, which, together with another recently reported paradigm of RNA editing-mediated feedback control, implicates a new role of RNA editing in fine-tuning biological outputs.
https://doi.org/10.1038/s41422-023-00834-y