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Spliceosome-associated quality control

Nikita Sharaev , Jiangfeng Zhao , Wojciech P. Galej

European Molecular Biology Laboratory, Grenoble, France
* Correspondence: Wojciech P. Galej(wgalej@embl.fr)

Intron removal from pre-mRNAs is one of the key steps in gene expression, but how it is achieved with high fidelity remains a subject of active research. Recent structural studies provide new insights into the spliceosome-mediated splice site proofreading mechanism.

https://doi.org/10.1038/s41422-025-01118-3

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