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Spliceosome-associated quality control
Nikita Sharaev , Jiangfeng Zhao , Wojciech P. Galej
European Molecular Biology Laboratory, Grenoble, FranceIntron removal from pre-mRNAs is one of the key steps in gene expression, but how it is achieved with high fidelity remains a subject of active research. Recent structural studies provide new insights into the spliceosome-mediated splice site proofreading mechanism.
https://doi.org/10.1038/s41422-025-01118-3