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Modeling mammalian hibernation to improve organ cold preservation: Using the intestine as an example

Weiya He^1,† , Ziqing He^1,† , Wenjun Deng^2,† , Chuman Wu^3,† , Wenjie Huang^3,† , Changhui Li³ , Yan Liang³ , Yifu Chen² , Renjie Luo⁴ , Yifei Zhao⁴ , Jiayu Liao³ , Xin Zhou⁴ , Guokai Chen^1,* , Ren-He Xu¹ , Meiling Liu^2,* , Ji Dong^3,*

¹Faculty of Health Sciences and UM-Bioland Joint Laboratory, University of Macau, Macau, China
²Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China
³GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macao Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou National Laboratory, Guangzhou Medical University, Guangzhou, Guangdong, China
⁴Department of General Surgery, Third Hospital, Peking University, Beijing, China
^†These authors contributed equally: Weiya He, Ziqing He, Wenjun Deng, Chuman Wu, Wenjie Huang
* Correspondence: Guokai Chen(guokaichen@um.edu.mo)Meiling Liu(liumling33@mail.sysu.edu.cn)Ji Dong(dong_ji@gzlab.ac.cn)

https://doi.org/10.1038/s41422-025-01149-w

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