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Constitutive arrestin recruitment by orphan GPR52 via an atypical binding mode

Xi Lin^1,†,* , Xiaohu Wei^2,† , Ning Pu^1,2,† , Ling Wang¹ , Zhibin Zhang^1,2 , Cuixia Li^1,2 , Yang Yue¹ , Junlin Liu¹ , Qiwen Tan¹ , Qianqian Sun¹ , Fei Xu^1,2,*

¹iHuman Institute, ShanghaiTech University, Shanghai, China
²School of Life Science and Technology, ShanghaiTech University, Shanghai, China
^†These authors contributed equally: Xi Lin, Xiaohu Wei, Ning Pu
* Correspondence: Xi Lin(linxi@shanghaitech.edu.cn)Fei Xu(xufei@shanghaitech.edu.cn)

https://doi.org/10.1038/s41422-025-01165-w

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