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Polycomb Repressive Complex 1 primes non-growing oocytes for growth and early embryogenesis

Mengwen Hu1,2,* , Yasuhisa Munakata1 , Yu-Han Yeh1 , Raissa G. Dani1 , Han Wang1 , Neil Hunter1,3 , Richard M. Schultz1,4 , Satoshi H. Namekawa1,*

1Department of Microbiology and Molecular Genetics, University of California, Davis, CA, USA
2Reproductive Medicine Center, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China
3Howard Hughes Medical Institute, University of California, Davis, CA, USA
4Department of Biology, University of Pennsylvania, Philadelphia, PA, USA
* Correspondence: Mengwen Hu(mwhu8860@163.com)Satoshi H. Namekawa(snamekawa@ucdavis.edu)

https://doi.org/10.1038/s41422-026-01232-w

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