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Decoding the regulatory grammar of human gene promoters

Zarnab Ahmad^1,* , Piero Carninci^2,3,*

¹Fred Hutchinson Cancer Center, Seattle, WA, USA
²Human Technopole, Milan, Italy
³RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
* Correspondence: Zarnab Ahmad(zahmad@fredhutch.org)Piero Carninci(piero.carninci@fht.org)

The recently developed promoter activity regulatory model (PARM) combines massively parallel reporter assays (MPRAs) with deep learning approaches to predict promoter activity across different human cell types.

https://doi.org/10.1038/s41422-026-01248-2

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