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A clearer view of PRSS56 in eyes with myopia

Nga T. Nguyen , Jeremy A. Guggenheim

School of Optometry & Vision Sciences, Cardiff University, Cardiff, UK
* Correspondence: Jeremy A. Guggenheim(GuggenheimJ1@cardiff.ac.uk)

The size and relative scaling of the eye’s component parts must be carefully orchestrated to achieve clear vision. Through studies of human pedigrees, mouse models and in vitro systems, Wu et al. reveal a central role for PRSS56 in this process, raising the profile of the gene as an attractive therapeutic target.

https://doi.org/10.1038/s41422-026-01250-8

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