Volume 22, No 8, Aug 2012

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 22 Issue 8, August 2012: 1210-1211

RESEARCH HIGHLIGHTS

Early exposure to germs and the Hygiene Hypothesis

Dale T Umetsu

Division of Immunology, Karp Laboratories, Rm 10127, Children's Hospital Boston, Harvard Medical School, One Blackfan Circle, Boston, MA 02115, USA Correspondence: Dale T Umetsu,(dale.umetsu@childrens.harvard.edu)

A recent paper suggests that reduced exposure to germs results in the expansion of a cell type called natural killer T cells, which predisposes to colitis and asthma. Such a scenario could explain the Hygiene Hypothesis, which has been a puzzle for decades.

Cell Research (2012) 22:1210-1211. doi:10.1038/cr.2012.65; published online 24 April 2012

FULL TEXT | PDF

Browse 1714