Volume 22, No 8, Aug 2012
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 22 Issue 8, August 2012: 1215-1217
RESEARCH HIGHLIGHTS
Will the real aging Sirtuin please stand up?
Chen-Yu Liao1 and Brian K Kennedy1,2
1Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USA
2Aging Research Institute, Guangdong Medical College, Dongguan, Guangdong 523808, China
Correspondence: Brian K Kennedy,(bkennedy@buckinstitute.org)
Initial studies linking Sirtuins to longevity in yeast initiated what is now a rich vein of aging research that is full of promise and fraught with controversy. Missing was a demonstration that enhanced Sirtuin expression extends lifespan in mammals. Now Kanfi et al. provide the evidence but with an interesting plot twist – the lesser known SIRT6 is the longevity factor.
Cell Research (2012) 22:1215-1217. doi: 10.1038/cr.2012.62; published online 17 April 2012
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