Volume 22, No 5, May 2012

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 22 Issue 5, May 2012: 789-790

RESEARCH HIGHLIGHTS

Mapping enhancer and promoter interactions

Jason Ernst^1,2

¹Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095-1737, USA
²Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, Los Angleles, CA 90095-7357, USA Correspondence: Jason Ernst,(jason.ernst@ucla.edu)

Histone modifications have previously been leveraged to map the locations of candidate enhancer and promoters in one dimensional genomic space. Chepelev et al. report the first Chromatin Interaction Analysis with Paired-End Tag (ChIA-PET) sequencing of a specific histone modification to systematically map long-range physical interactions among enhancer and promoters, yielding insights into the nature of these interactions.

Cell Research (2012) 22:789-790. doi:10.1038/cr.2012.49; published online 27 March 2012

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