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Volume 22, No 3, Mar 2012

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 22 Issue 3, March 2012: 443-446

RESEARCH HIGHLIGHTS

Breathless cancer cells get fat on glutamine

Dimitrios Anastasiou and Lewis C Cantley

Beth Israel Deaconess Medical Center, Department of Medicine-Division of Signal Transduction; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA Correspondence: (lewis_cantley@hms.harvard.edu)

Many cancer cells depend on glutamine as a fuel for proliferation, yet the mechanisms by which glutamine supports cancer metabolism are not fully understood. Two recent studies highlight an important role for glutamine in the synthesis of lipids and provide novel insights into how glutamine metabolism could be targeted for cancer therapy.


Cell Research (2012) 22:443-446. doi:10.1038/cr.2012.5; published online 3 January 2012

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