Volume 21, No 4, Apr 2011
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 21 Issue 4, April 2011: 564-578
REVIEWS
Readers of histone modifications
Miyong Yun1, Jun Wu1, Jerry L Workman2 and Bing Li1
1Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390-9148, USA;
2Stowers Medical Research Institute, Kansas City, MO 64110, USA
Correspondence: Bing Li,(Bing4.Li@utsouthwestern.edu)
Histone modifications not only play important roles in regulating chromatin structure and nuclear processes but also can be passed to daughter cells as epigenetic marks. Accumulating evidence suggests that the key function of histone modifications is to signal for recruitment or activity of downstream effectors. Here, we discuss the latest discovery of histone-modification readers and how the modification language is interpreted.
Cell Research (2011) 21:564-578. doi:10.1038/cr.2011.42; published online 22 March 2011
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