Volume 16, No 2, Feb 2006

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 16 Issue 2, February 2006: 214-219

REVIEWS

STAT3 in immune responses and inflammatory bowel diseases

Xin Yuan Fu

Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, 635 Barnhill Drive, MS 420, Indianapolis, IN 46202-5120, USA Correspondence: Xin Yuan Fu(xfu@IUPUI.edu)

STAT3 has been known as a mediator for gene expression induced by many important cytokines. Recent studies have suggested that STAT3 has important functions in regulation of both innate and adaptive immunity. Loss of STAT3 in immune cells caused severe inflammation in response to pathogens. This review discusses the recent progress and suggests directions for the future research on this interesting molecule.

Cell Research (2006) 16:214-219. doi:10.1038/sj.cr.7310029; published online 13 February 2006

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