Volume 15, No 2, Feb 2005
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 15 Issue 2, February 2005: 97-98
LETTERS TO THE EDITOR
SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
Yong Yong Shi1,2, Lin He2,3,*
1Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, China;
2Institute for Nutritional Sciences, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences, Shanghai, China;
3NHGG, Bio-X Center, Shanghai Jiao Tong University, Shanghai, China
Correspondence: Lin He(helin@nhgg.org)
In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.
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