Volume 12, No 2, Jun 2002

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 12 Issue 2, June 2002: 97-104

REVIEWS

Targeting epidermal Langerhans cells by epidermal powder immunization

Dexiang CHEN*, Lendon G PAYNE

PowderJect Vaccines, Inc. 585 Science Drive, Madison, WI 53711, USA Correspondence:

Immune reactions to foreign or self-antigens lead to protective immunity and, sometimes, immune disorders such as allergies and autoimmune diseases. Antigen presenting cells (APC) including epidermal Langerhans cells (LCs) play an important role in the course and outcome of the immune reactions. Epidermal powder immunization (EPI) is a technology that offers a tool to manipulate the LCs and the potential to harness the immune reactions towards prevention and treatment of infectious diseases and immune disorders.

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