Volume 11, No 1, Mar 2001
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 11 Issue 1, March 2001: 1-7
REVIEWS
Apoptosis in oncology
Fan Xiao Qiang, Ya Jun Guo*
International Joint Cancer Institute, The Second Military Medical University, Shanghai 200433, China
Correspondence:
Apoptosis is a complex process involving a large array of genes and mutation of any of these genes may lead to malignancy formation. Re-acquirement of FasL by tumor cells may enable them to evade the surveillance of immune system and thus contributes to the growth of tumor. Apart from traditional therapies, inducing apoptosis of tumor cell by new methods employing death receptor ligands and making use of Fas counterattack is also being developed.
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