Volume 23, No 3, Mar 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 3, March 2013: 311-313

RESEARCH HIGHLIGHTS

Non-coding transcription SETs up regulation

Swaminathan Venkatesh¹ and Jerry L Workman¹

¹Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA Correspondence: Jerry L Workman(JLW@stowers.org)

An abundance of long non-coding RNA (lncRNA) present in most species from yeast to human are involved in transcriptional regulation, dosage compensation and imprinting. This underscores the importance of lncRNA as functional RNA despite the fact that they do not produce proteins. Two recent papers in Cell have demonstrated that transcription of the non-conserved lncRNAs, but not the RNAs themselves, is necessary to introduce co-transcriptional regulatory histone marks to regulate gene expression.

Cell Research (2013) 23:311–313; doi:10.1038/cr.2012.147; published online 13 November 2012

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