Volume 23, No 3, Mar 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 3, March 2013: 323-325

RESEARCH HIGHLIGHTS

Dendritic self-avoidance: protocadherins have it covered

Phuong Hoang^1,2 and Wesley B Grueber^1,2

¹Department of Neuroscience, Columbia University Medical Center, 630 W. 168th St. P&S 12-403, New York, NY 10032, USA
²Department of Physiology and Cellular Biophysics, Columbia University Medical Center, 630 W. 168th St. P&S 12-403, New York, NY 10032, USA
Correspondence: Wesley B Grueber(wg2135@columbia.edu)

Dendrites exhibit self-avoidance, in which branches of the same neuron repel each other while overlapping with branches from neighboring neurons. A recent paper by Lefebvre and colleagues reveals that clustered protocadherins provide a basis for neuronal recognition during dendrite self-avoidance in vertebrates.

Cell Research (2013) 23:323–325; doi:10.1038/cr.2012.137; published online 18 September 2012

FULL TEXT | PDF

Browse 2095