Volume 23, No 4, Apr 2013
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 23 Issue 4, April 2013: 452-454
RESEARCH HIGHLIGHTS
Fox family ties
Calvin B Williams1 and Talal A Chatila2
1Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
2Division of Immunology, the Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
Correspondence: Calvin B Williams(cwilliam@mcw.edu)
The transcription factor Foxp3 plays an indispensible role in the differentiation of regulatory T (Treg) cells and the expression of their suppressive functions. In a recent article published in Nature, Ouyang et al. demonstrate that Treg cell differentiation is also enabled by transcriptional networks controlled by another Forkhead box family member, Foxo1.
Cell Research (2013) 23:452–454. doi:10.1038/cr.2013.5; published online 15 January 2013
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