Volume 23, No 4, Apr 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 4, April 2013: 455-457

RESEARCH HIGHLIGHTS

Losing stem cells in the aged skeletal muscle niche

Shahragim Tajbakhsh

Stem Cells and Development, Department of Developmental & Stem Cell Biology, CNRS URA 2578, Pasteur Institute, 25 rue du Dr. Roux, 75015, Paris, France Correspondence: Shahragim Tajbakhsh(shaht@pasteur.fr)

Why stem cell numbers decline with age is a major question in regenerative biology and medicine. Skeletal muscle has emerged as a powerful paradigm to address this issue. Recently, genetic and cell marking strategies were used to uncover a new and causal relationship between muscle stem cells and differentiated fibers that constitute their niche and provoke their loss.

Cell Research (2013) 23:455–457. doi:10.1038/cr.2013.3; published online 1 January 2013

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