Volume 23, No 4, Apr 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 4, April 2013: 460-462

RESEARCH HIGHLIGHTS

Mucosal associated invariant T cells: Don't forget your vitamins

Mary H Young and Laurent Gapin

Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, CO 80206, USA Correspondence: Laurent Gapin(gapinl@njhealth.org)

T lymphocytes express clonal receptors, called T cell receptors (TCRs), which specifically recognize antigens presented in combination with major histocompatibility molecules (MHC). To date, T cell antigens can be broadly categorized into two classes: peptides and lipids. A recent paper published in Nature by Kjer-Nielsen and colleagues reveals that a unique population of T lymphocytes expresses TCRs that recognize a completely new and unexpected class of antigens, vitamin metabolites.

Cell Research (2013) 23:460–462. doi:10.1038/cr.2012.168; published online 4 December 2012

FULL TEXT | PDF

Browse 1980