Volume 23, No 5, May 2013
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 23 Issue 5, May 2013: 588-589
RESEARCH HIGHLIGHTS
Death at the airway epithelium in asthma
Bart N Lambrecht1,2,3 and Hamida Hammad1,2
1Department for Molecular Biomedical Research, VIB, Gent, Belgium
2Department of Pulmonary Medicine, Ghent University, Ghent, Belgium
3Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
Correspondence: Bart N Lambrecht(bart.lambrecht@ugent.be)
Allergic asthma is an inflammatory disease of the airways in which epithelial cells, dendritic cells and innate lymphoid cells are increasingly implicated. Recent findings suggest that apoptotic cells are phagocytosed by airway epithelial cells in a Rac1-dependent manner and this leads to dampening of innate and adaptive immunity to allergens.
Cell Research (2013) 23:588–589. doi:10.1038/cr.2013.26; published online 19 February 2013
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