Volume 1 Issue 1, March 1990: 77-87
ORIGINAL ARTICLES
Effect of peripheral nerve on the neurite growth from retinal explants in culture
Li Liu1 and Kwokfai So2
1Shanghai Institute of Cell Biology, Academia Sinica, Shanghai, China
2Department of Anatomy, University of Hong Kong, Hong Kong
Correspondence: Liu Li
The effect of peripheral nerve (PN)on neurite outgrowth from retinal explants of adult hamsters was examined. Cultures of retinal explants, and co-cultures of retinal explants and PN were performed using chick retinal basement membrane (BM) as substrate. The presence of PN increases the number and length of neurite outgrowth. In addition, a high proportion of neurites situated close to PN tend to grow towards it. Since there was no contact between retinal explants and PN, we suggest that PN might secrete diffusible substances to attract the neurites to grow towards it.
Cell Res 1: 77-87; doi:10.1038/cr.1990.8
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