Volume 23, No 7, Jul 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 7, July 2013: 874-875

RESEARCH HIGHLIGHTS

ALDH2, a novel target for endogenous neuroprotection against stroke?

Aijun Sun^1,2 and Jun Ren^1,2

¹Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
²Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, WY 82071, USA Correspondence: Jun Ren, Tel: 1-307-766-6131; Fax: 1-307-766-2953(jren@uwyo.edu)

In a recent paper published in Cell Research, an association between expression of mitochondrial aldehyde dehydrogenase (ALDH2), a mitochondrial chaperon expressed in the brain, and the prevalence of stroke is revealed. This finding indicates that ALDH2 may serve as a potential endogenous neuroprotective target and a promising therapeutic strategy for the management of stroke.

10.1038/cr.2013.76

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