Volume 23, No 12, Dec 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 12, December 2013: 1414-1416

LETTERS TO THE EDITOR

The CRISPR/Cas System mediates efficient genome engineering in Bombyx mori

Yueqiang Wang^1,2, Zhiqian Li^1,2, Jun Xu^1,2, Baosheng Zeng^1,2, Lin Ling¹, Lang You¹, Yazhou Chen¹, Yongping Huang¹ and Anjiang Tan¹

¹Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
²University of Chinese Academy of Sciences, Beijing 100049, China Correspondence: Yongping Huang, E-mail: yphuang@sibs.ac.cn Tel: +86-21-54924047; Fax: +86-21-54924015; Anjiang Tan,(tananjiang@sippe.ac.cn)

Insect genome engineering is crucial for gene functional analysis and the long-term development of novel pest control technologies. The recently developed engineered nucleases, zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs), are capable of facilitating precise genome modifications1.

10.1038/cr.2013.146

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