Volume 23, No 12, Dec 2013

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 23 Issue 12, December 2013: 1417-1419

LETTERS TO THE EDITOR

Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase

Shannon Nangle^1,*, Weiman Xing^1,2,* and Ning Zheng^1,2

¹Department of Pharmacology, University of Washington, Seattle, WA 98195, USA
²Howard Hughes Medical Institute, Box 357280, University of Washington, Seattle, WA 98195, USA Correspondence: Weiman Xing, E-mail: wxing@uw.edu; Ning Zheng(nzheng@uw.edu)

The cryptochrome (CRY) flavoproteins are critical components of the mammalian molecular circadian clock, which operates through an auto-regulatory transcription-translation feedback loop1.

10.1038/cr.2013.136

FULL TEXT | PDF

Browse 1933