Volume 24, No 5, May 2014
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 24 Issue 5, May 2014: 636-639
LETTERS TO THE EDITOR
Beadex affects gastric emptying in Drosophila
Jing Ren1,3, Huanhu Zhu1, Chongwu Chi1, Mahya Mehrmohamadi2, Kejing Deng1, Xiaohui Wu1 and Tian Xu1,2
1State Key Laboratory of Genetic Engineering and National Center for International Research of Development and Disease, Collaborative Innovation Center for Genetics and Development, Fudan-Yale Biomedical Research Center, Institute of Developmental Biology and Molecular Medicine, School of Life Sciences, Children's Hospital, Fudan University, Shanghai 200433, China
2Howard Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06536, USA
3Current address: State Key Laboratory of Dairy Biotechnology, Dairy Research Institute, Bright Dairy & Food Co., Ltd. Bldg. 2, No.1518, West Jiangchang Road, Shanghai 200436, China
Correspondence: Tian Xu, E-mail: tian.xu@yale.edu; Xiaohui Wu,(xiaohui_wu@fudan.edu.cn)
The ingestion and digestion of food is a universal aspect of animal growth and survival and is important for our understanding of obesity and diabetes. All animals have a digestive system that comprises of an upper gastrointestinal tract mainly for the ingestion and storage of food, and a lower gastrointestinal tract or the gut for digestion and absorption. When food is ingested, peristaltic contraction is initiated and directs the bolus through the esophagus toward the stomach or an equivalent structure1. In addition to serving as the major site for digestion, the stomach acts as a reservoir to store food. This adaptation may have significance for the survival of many animals in which the immediate access to the infrequent availability of food necessitates large meal consumptions that can then be slowly digested or utilized at a later time. Once the food is triturated in the stomach, it is released into the lower gut where the main function of digestion and absorption of nutrients is carried out.
10.1038/cr.2014.24
FULL TEXT | PDF
Browse 1834
