Volume 24, No 7, Jul 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 7, July 2014: 775-776

RESEARCH HIGHLIGHTS

Mediator redefines itself

Nicholas C Sennett¹ and Dylan J Taatjes¹

¹Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80303, USA Correspondence: Dylan J Taatjes, Tel: +1 303 492-6929; Fax: +1 303 492-5894(Taatjes@colorado.edu)

Mediator is a large and structurally dynamic protein complex that is globally required for eukaryotic transcription by RNA polymerase II. In a recent paper published in Cell Research, Wang et al. report for the first time the location of distinct subunits and redefine domains in the S. cerevisiae Mediator complex.

10.1038/cr.2014.76

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