Volume 24, No 7, Jul 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 7, July 2014: 779-780

RESEARCH HIGHLIGHTS

piRNAs, master regulators of gene expression

Martine Simonelig¹

¹mRNA Regulation and Development, Institute of Human Genetics, CNRS UPR1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France Correspondence: Martine Simonelig, Tel: 33 4 34 35 99 59; Fax: 33 4 34 35 99 57(Martine.Simonelig@igh.cnrs.fr)

Piwi-interacting RNAs (piRNAs) have a major function in the repression of transposable elements in the germline; in addition, they have been proposed to regulate gene expression. A recent study in Cell Research reveals a general role for piRNAs in the massive mRNA decay during mouse spermiogenesis, reinforcing this emerging function of piRNAs.

10.1038/cr.2014.78

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