Volume 24, No 8, Aug 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 8, August 2014: 906-907

RESEARCH HIGHLIGHTS

Linking SOX10 to a slow-growth resistance phenotype

Gao Zhang^1,2 and Meenhard Herlyn^1,2

¹Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA
²Melanoma Research Center, The Wistar Institute, Philadelphia, PA 19104, USA Correspondence: Meenhard Herlyn,(herlynm@wistar.org)

Slow-cycling BRAFV600E melanoma cells are notoriously resistant to standard chemotherapy or targeted therapy but the underlying mechanism remains elusive. Now a new study unlocks this mystery and offers novel insights into developing more effective therapeutic interventions.

10.1038/cr.2014.67

FULL TEXT | PDF

Browse 1703