Volume 24, No 8, Aug 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 8, August 2014: 908-909

RESEARCH HIGHLIGHTS

Regulating the regulator of ROS production

Marcelo G Bonini^1,2,3 and Asrar B Malik^1,4

¹Department of Pharmacology, The University of Illinois College of Medicine, 835 South Wolcott Avenue, Chicago, IL 60612, USA
²Department of Medicine, The University of Illinois College of Medicine, 835 South Wolcott Avenue, Chicago, IL 60612, USA
³Department of Pathology, The University of Illinois College of Medicine, 835 South Wolcott Avenue, Chicago, IL 60612, USA
⁴Center for Lung and Vascular Biology, The University of Illinois College of Medicine, 835 South Wolcott Avenue, Chicago, IL 60612, USA Correspondence: Asrar B Malik,(abmalik@uic.edu)

Balancing inflammatory reactive oxygen species (ROS) production is essential for safely eliminating pathogenic microbes. The newly described protein Negative Regulator of ROS (NRROS) dampens ROS production by restricting NOX2 availability, and thus “cools-off” inflammation.

10.1038/cr.2014.66

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