Volume 24, No 8, Aug 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 8, August 2014: 910-911

RESEARCH HIGHLIGHTS

The soft underbelly of tumor cells

Yufeng Shi¹, S Kyun Lim¹ and Luis F Parada¹

¹Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA Correspondence: Luis F Parada,(luis.parada@utsouthwestern.edu)

In a recent Cell paper, Kitambi and colleagues identify a small molecule (Vacquinol-1) that has beneficial effects on a glioblastoma multiforme mouse model by oral administration. In glioblastoma cells, Vacquinol-1 targets macropinocytosis, a cellular process that will not lead to cell death in normal cells.

10.1038/cr.2014.72

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