Volume 24, No 10, Oct 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 10, October 2014: 1151-1152

RESEARCH HIGHLIGHTS

Blood loses it when nerves go bad

Ninib Baryawno^1,2,3 and David T Scadden^1,2,3

¹Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
²Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
³Harvard Stem Cell Institute, Cambridge, MA 02138, USA Correspondence: David T Scadden,(david_scadden@harvard.edu)

Myeloproliferative neoplasms are diseases that arise in the stem cells of the blood. In a recent paper published in Nature, Arranz et al. demonstrated that abrogation of sympathetic nerve fibers reduced bone marrow Nestin+ mesenchymal cells, which in turn led to an expansion of hematopoietic stem cells and progression of myeloproliferative neoplasms.

10.1038/cr.2014.98

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