Volume 24, No 10, Oct 2014
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 24 Issue 10, October 2014: 1153-1154
RESEARCH HIGHLIGHTS
A new HCV mouse model on the block
Rajiv G Tawar1,2, Laurent Mailly1,2 and Thomas F Baumert1,2,3
1Inserm, U1110, Strasbourg, France
2Université de Strasbourg, Strasbourg, France
3Pôle Hépato-digestif, Institut Hospitalo-Universitaire, Strasbourg, France
Correspondence: Thomas F Baumert, Tel: (33) 368853703; Fax: (33) 368853750(Thomas.Baumert@unistra.fr)
The investigation of virus-induced liver disease and hepatocellular carcinoma needs small animal models modeling hepatitis C virus (HCV) infection and liver disease biology. A recent study published in Cell Research reports a novel mouse model which is permissive for chronic HCV infection and shows chronic liver injury including inflammation, steatosis and fibrosis.
10.1038/cr.2014.126
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